Potassium chloroplatinite is a chemical with the formula K2PtCl4. This substance is a coordination compound in which the platinum atom is located in the center and surrounded by four chloride ions and two potassium ions. It is a precursor of platinum-based anticancer drugs and has important applications in chemical and pharmaceutical research.
Physical and chemical properties:
Appearance properties Red crystalline solid
Melting point 250°C
Density 3.38 g/mL at 25 °C(lit.)
Water solubility 10 g/L (20 ºC)
Production method:
Preparation method: Platinum dichloride is dissolved in hydrochloric acid to form tetrachloroplatinum (Ⅱ) acid, adding potassium chloride and cooling with ice water.
In the field of medicine, by reacting potassium chloroplatinite with other compounds, a variety of platinum-based anticancer drugs, such as cisplatin, can be prepared. This class of drugs inhibits the proliferation of cancer cells and induces cell death by forming cross-links with DNA and blocking DNA replication and transcription of cancer cells.
Potassium chloroplatinite itself is usually present in solid form and needs to be synthesized and purified by precise chemical reaction processes in the laboratory or industrial production. Because of its key role in the synthesis of anticancer drugs, this substance is very important in the process of pharmaceutical chemistry research and drug development.
It is important to note that care must be taken when handling and using potassium chloroplatinite, as it can be hazardous to human health, especially to the skin and respiratory system. Appropriate safety measures should be taken when used in laboratory and industrial environments.
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Wisdomdrugs Co., LTD., founded in September 2011, is headquartered in Changzhou Hang Seng Science and Technology Industrial Park. Today, the company’s R&D center is engaged in the process research and development, production, optimization, custom synthesis and technology transfer of API or pharmaceutical intermediates, plant extracts, compounds from laboratory scale to commercial scaleup production, to meet the growing requirements of customers.
The company focuses on the protection of intellectual property rights, continuous invention and innovation research and development of production processes, to avoid the regulatory market patent and intellectual property issues, perfect impurity research, to provide customers with a full set of CMC or DMF registration documents.
