Intermediates usually refer to some of the chemicals used in the manufacturing of medical beauty products, which are key ingredients in the final product, but may require further processing or mixing with other ingredients to form the final product. Intermediates can be varied, including but not limited to the following types:
1. Peptides: For example, hexapeptide-11, pentapeptide-4, etc. used in anti-aging products, which help to reduce wrinkles and fine lines and promote smooth skin.
Polypeptide intermediates play an important role in medical and beauty products, mainly because they have the function of imitating natural bioactive peptides, which can promote skin repair, regeneration and anti-aging effects. They are short chain molecules formed by amino acids connected by peptide bonds, and different peptide sequences can be designed according to different formulations and purposes. Here are some common polypeptide intermediates and their applications:
1. Copper tripeptide (GHK-Cu) : This is a peptide composed of three amino acids, combined with copper ions to form a complex. It has the effect of promoting wound healing, stimulating collagen and elastin production, and is widely used in anti-aging and repair products.
2. Amino acid oligopeptides (such as Pal-KTTKS, or Matrixyl) : This peptide can promote the production of more collagen in the skin, thereby reducing fine lines and wrinkles and increasing the elasticity and firmness of the skin.
3. Acetylhexapeptide-8 (Argireline) : It mimics the function of neuropeptides to slow down muscle contractions, thus reducing the formation of expression marks, and is a non-invasive alternative to Botox.
4. Pentapeptide-4 (SYN-COLL) : This peptide can mimic the process of collagen production in the human body, so as to stimulate the skin to produce more collagen, which has a good anti-aging effect.
5. Hexapeptide-9 (Syn-Ake) : mimics the peptide in snake venom, which can relax muscles and reduce the formation of dynamic lines.
These polypeptide intermediates are usually synthesized in the laboratory by solid-phase or liquid-phase peptide synthesis, and the synthesized peptides are purified, folded into the correct three-dimensional structure, and subjected to strict quality control. When applied to medical beauty products, they are usually used in a stable form in conjunction with other ingredients to ensure optimal results and safety on the skin.
2. Organic acids: such as hyaluronic acid, fruit acid, etc., they have significant effects in moisturizing and skin renewal.
3. Vitamins: such as vitamin C (antioxidants), vitamin E, etc., used to enhance the skin’s natural protective ability.
4. Plant extracts: Various plant extracts, such as green tea extract, grape seed extract, etc., often have antioxidant, anti-inflammatory or other beneficial properties for the skin.
5. Biotechnology products: such as various bioactive molecules produced by fermentation processes.
In the specific medical beauty product development and production process, these intermediates need to meet strict quality standards and safety requirements to ensure the effect and safety of the final product. Pharmaceutical companies and cosmetic manufacturers often source these substances from specialist intermediate suppliers and rigorously test them during product development.